Publications par axes

AXE 4

Liste des publications 2012-2014

   

Les équipes impliquées :

1 = Equipe TRYPSIN (CNRS Gif/Yvette)
2 = Unité Toxicologie des contaminants (Anses Fougères)
3 = PHYC, Ifremer Nantes
4 = Unité Pesticides et Biotoxines marines (Anses Maisons Alfort)

2014 :

  • FERRON, P.-J., HOGEVEEN, K, Fessard, V, Le Hégarat, L. (2014). Comparative analysis of the cytotoxic effects of okadaic acid-group toxins on human intestinal cell lines. Mar Drugs. 12(8):4616-34 (Equipe 2)
  • Fessard, V. (2014). Toxicity of okadaic acid/dinophysistoxins and microcystins on biological systems. In: Toxins and biologically active compounds from microalgae. Vol. 2: Biological Effects and Risk Management.  G.P. Rossini (Ed). CRC Press Inc. Taylor & Francis Inc., Boca Raton, Florida, USA, pp. 253-282. ISBN 9781482231465. (Equipe 2)
  • Fleming, L.E., MC Donough, N., Austen, M., L, M., Moore, M., Hess, P., Depledge, M.H., White, M., Philippart, K., Bradbrook, P., Smalley, A. (2014). Oceans and Human Health: A Rising Tide of Challenges and Opportunities for Europe. Mar. Environ. Res. 2014, 99, 16-19. (Equipe 3)
  • Kittler K., Fessard, V., Maul, R., Hurtaud-Pessel, D. (2014). CYP3A4 activity reduces the cytotoxic effects of okadaic acid in HepaRG cells. Arch Toxicol 88(8):1519-26 (Equipe 2)
  • Henri,  J., Leighfield, T.A., Lanceleur, R., Huguet, A., Ramsdell, J. S., Fessard, V. (2014). Permeability of dihydro- and cysteine-brevetoxin metabolites across a Caco-2 cell monolayer. Harmful Algae 32 : 22-26  (Equipe 2)
  • MATTEI, C., MOLGÓ, J., BENOIT, E. (2014). Involvement of both sodium influx and potassium efflux in ciguatoxin-induced nodal swelling of frog myelinated axons. Neuropharmacology, 85: 417-426. doi:10.1016/j.neuropharm.2014.06.001. (F.I. = 4,819) (Equipe 1)
  • MOLGO, J., ARAOZ, R., BENOIT, E., IORGA, B.I. (2014). Cyclic imine toxins: chemistry, origin, metabolism, pharmacology, toxicology, and detection. In:  Seafood and Freshwater Toxins: Pharmacology, Physiology, and Detection. Third Edition. L.M. Botana (Ed.). Taylor and Francis, LLC, Boca Raton, Florida USA, pp. 951-989. ISBN 9781466505148.  (Equipe 1)
  • MOLGO, J., ARAOZ, R., IORGA, B.I., BENOIT, E., ZAKARIAN, A. (2014). Cyclic imine neurotoxins acting on muscarinic and nicotinic acetylcholine receptors. In: Toxins and biologically active compounds from microalgae. Vol. 2: Biological Effects and Risk Management.  G.P. Rossini (Ed). CRC Press Inc. Taylor & Francis Inc., Boca Raton, Florida, USA, pp. 116-146. ISBN 9781482231465. (Equipe 1)
  •  RUBIO, F., KAMP, L., CARPINO, J., FALTIN, E., LOFTIN, K., MOLGÓ, J., ARÁOZ, R. (2014). Colorimetric microtiter plate receptor-binding assay for the detection of freshwater and marine neurotoxins targeting the nicotinic acetylcholine receptors. Toxicon (sous presse), doi: 10.1016/j.toxicon.2014.08.073. (F.I. = 2,581) (Equipe 1)
  • STIVALA, C.E., BENOIT, E., ARÁOZ, R., SERVENT, D., NOVIKOV, A., MOLGÓ, J., ZAKARIAN, A. (2014). Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins. Nat. Prod. Rep., (in press) DOI: 10.1039/C4NP00089G. (F.I. = 10,715) (Equipe 1)

 

2013

  • DANESHIAN, M., BOTANA, L.M., DECHRAOUI BOTTEIN, M.Y., BUCKLAND, G., CAMPÀS, M., DENNISON, N., DICKEY, R.W., DIOGENE, J., FESSARD, V., HARTUNG, T., HUMPAGE, A., LEIST, M., MOLGO, J., QUILLIAM, M.A., ROVIDA, C., SUAREZ-ISLA, B.A., TUBARO, A., WAGNER, K., ZOLLER, O., DIETRICH, D. (2013). A roadmap for hazard monitoring and risk assessment of marine biotoxins on the basis of chemical and biological test systems. ALTEX, 30(4): 487-545. (I.F. = 3,63) (Equipe 1+2)
  • Geiger, M., Desanglois, G., Hogeveen, K., Fessard, V., Leprêtre, T., Mondeguer F., Guitton, Y., Hervé, F., Séchet, V., Grovel, O., Pouchus, Y-F., Hess, P. (2013). Cytotoxicity, fractionation and dereplication of extracts of the dinoflagellate Vulcanodinium rugosum, a producer of Pinnatoxin G. Mar. Drugs, 11, 3350-3371 (Equipes 1+3)
  • GRANDI?, M., ARÁOZ, R., MOLGO, J., TURK, T., SEP?I?, K., BENOIT, E., FRANGE?, R. (2013). Toxicity of the synthetic polymeric 3-alkylpyridinium salt (APS3) is due to specific block of nicotinic acetylcholine receptors. Toxicology, 303C: 25–33. doi: 10.1016/j.tox.2012.10.013. (F.I. = 3,745)  (Equipe 1)
  • HESS, P., ABADIE, E., HERVÉ, F., BERTEAUX, T., SÉCHET, V., ARÁOZ, R., MOLGÓ, J., ZAKARIAN, A., SIBAT, M., RUNDBERGET, T., MILES, C.O., AMZIL, Z. (2013). Pinnatoxin-G is responsible for atypical toxicity in mussels (Mytilus galloprovincialis) and clams (Venerupis decussata) from Ingril, a French Mediterranean lagoon. Toxicon, 75: 16-26. doi:. 10.1016/ j.toxicon.2013.05.001. (F.I. = 2.924)  (Equipes 1 + 3)
  • MARROUCHI, R., BENOIT, E., LE CAER, J-P., BELAYOUNI, N., BELGHITH, H., MOLGO, J., KHARRAT, R. (2013). Toxic C17-sphinganine analogue mycotoxin, contaminating Tunisian mussels, causes flaccid paralysis in rodents.  Mar. Drugs, 11: 4724-4740; doi:10.3390/md11124724 (F.I. = 3,978).  (Equipe 2)
  • MARROUCHI, R., ROME, G., KHARRAT, R., MOLGO, J., BENOIT, E. (2013). Analysis of the action of gymnodimine-A and 13-desmethyl spirolide C on the mouse neuromuscular system in vivo. Toxicon, 75: 27-34. doi: 10.1016/j.toxicon.2013.08.050. (F.I. = 2.924) (Equipe 1)
  • MOLGO, J., ARAOZ, R., BENOIT, E., IORGA, B.I. (2013). Physical and virtual screening methods for marine toxins and drug discovery targeting nicotinic acetylcholine receptors. Expert. Opin. Drug Discov., 8(10): 1203-1223. doi: 10.1517/17460441.2013.822365. (F.I. = 2,297)  (Equipe 1)
  • PÉREZ RODRÍGUEZ L., VILARIÑO, N., MOLGO, J., ARAOZ, R., LOUZAO, M.C., TAYLOR, P., TALLEY, T., BOTANA, L.M. (2013). Development of a solid-phase receptor-based assay for the detection of cyclic imines using a microsphere-flow cytometry system. Anal. Chem., 85: 2340-2347. doi: 10.1021/ac3033432. (F.I. = 5, 825) (Equipe 1)
  • RODRÍGUEZ, L.P., VILARIÑO, N., MOLGO, J., ARAOZ, R., BOTANA, L.M. (2013). High-throughput receptor-based assay for the detection of spirolides by chemiluminescence. Toxicon, 75: 35-43. doi:pii: 10.1016/j.toxicon.2013.06.015. (F.I. = 2,924) (Equipe 1)

 

2012:

  • ARAOZ, R., RAMOS, S., PELISSIER, F., GUÉRINEAU, V., BENOIT, E., VILARIÑO, N., BOTANA, L.M., ZAKARIAN, A., MOLGO, J. (2012). Coupling the Torpedo microplate receptor-binding assay with mass spectrometry to detect cyclic imine neuro-toxins. Anal. Chem., 84(23): 10445–10453.DOI: 10.1021/ac3027564.  (I.F. = 5,856). (Equipe 1)
  • Aune, T., Espenes, A., Aasen, J.A.B., Walter, J., Quilliam, M.A., Hess, P., Larsen S. (2012). Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route. Toxicon 60 895-906.( Equipe 3)
  • DEL FAVERO, G., FLORIO, C., CODAN, B., SOSA, S., POLI, M., SBAIZERO, O., MOLGO, J., TUBARO, A., LORENZON, P.  (2012). The stretch-activated channel blocker Gd3+ reduces palytoxin toxicity in primary cultures of skeletal muscle cells. Chem. Res. Toxicol., 25: 1912−1920. F.I. = 3.779 (Equipe 1)
  • GRANDI?, M., ARÁOZ, R., MOLGÓ, J., SEP?I?, K., TURK, T., BENOIT, E., FRANGE?, R. (2012). The non-competitive acetylcholinesterase inhibitor APS12-2 is a potent antagonist of skeletal muscle nicotinic acetylcholine receptors. Toxicol. Appl. Pharmacol., 265: 221–228.  I.F. = 3,991 (Equipe 1)
  • JACKSON, J.J., STIVALA, C.E., IORGA, B.I., MOLGO, J., ZAKARIAN, A. (2012). Stability of cyclic imine toxins: interconversion of pinnatoxin amino ketone and pinnatoxin A in aqueous media. J. Org. Chem., 77: 10435−10440. I.F. = 4,450 (Equipe 1)
  • Ledreux, A., Fessard, V., Krys, S., Troussellier, M., Bernard, C. (2012). Response to Letter to the Editor regarding “Collaborative study for the detection of toxic compounds in shellfish extracts using cell-based assays. Part I: screening strategy and pre-validation study with lipophilic marine toxins” and “Part II: application to shellfish extracts spiked with lipophilic marine toxins.” Analytical and Bioanalytical Chemistry 404 (5) : 1613-1614 (Equipes 2+4)
  • Ledreux, A., Sérandour, A.-L., Morin, B., Derick, S., Lanceleur, R., Hamlaoui, S., Furger, C., Krys, S., Biré, R., Fessard, V., Troussellier, M., Bernard, C. (2012). Collaborative study for the detection of toxic compounds in shellfish extracts using cell based-assays. Part II: application to shellfish extracts spiked with lipophilic marine toxins. Analytical and Bioanalytical Chemistry, 403(7):1995-2007 (Equipes 2+4)
  • Mondeguer, F., Antignac, J.P., Guitton, Y., Monteau, F., LeBorgne, S., Hess, P. (2012). Nouvelle stratégie de caractérisation non ciblée de type métabolomique au service de l’identification de composés bioactifs accumulés dans les mollusques bivalves. Spectra Analyse 284 (3) 24-33. (Equipe 3)
  • Sérandour, A.-L., Ledreux, A., Morin, B., Derick, S., Augier, E., Lanceleur, R., Hamlaoui, S., Moukha, S., Furger, C., Biré, R., Fessard, V., Troussellier, M., Bernard, C. (2012). Collaborative study for the detection of toxic compounds in shellfish extracts using cell based-assays. Part I: screening strategy and prevalidation study with pure lipophilic marine toxins. Analytical and Bioanalytical Chemistry, 403(7):1983-93 (Equipes 2+4)
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